Understanding eczema in babies
As a parent, few things are more upsetting than witnessing a baby with eczema scratch, cry, and lose sleep. According to some research, almost 30% of babies in the UK are diagnosed with eczema (also known as atopic dermatitis) by the time they become one year old.
The gut microbiome, a complex ecosystem of bacteria in the digestive tract, may have an impact on immune development and skin health from the first few months of life, despite the fact that traditional treatments (such as emollients and steroids) concentrate on lowering skin inflammation.
This has sparked curiosity on whether microbiome testing can assist parents in understanding the causes of eczema and how to lessen its severity, particularly during the first 1,000 days when gut flora and the immune system change quickly.
Why the Gut-Skin Connection Is Important
The gut–skin axis, a mechanism that connects gut bacteria to inflammation and immunological responses throughout the body, including the skin, is how the gut microbiome interacts with the immune system, according to research.

When compared to babies without eczema, infants with eczema frequently exhibit clear variations in the composition of their gut microbiota. For instance:
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Babies with eczema may have lower levels of some good bacteria, such as Bifidobacterium and Faecalibacterium, which are known to maintain the integrity of the gut barrier.
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On the other hand, some research has connected eczema with increased amounts of bacteria from the Enterobacteriaceae family, which can cause inflammation. https://pmc.ncbi.nlm.nih.gov/articles/PMC5094743/
These variations imply that eczema severity or development may be influenced by abnormalities in the early gut flora.
Infant Eczema in the UK: The Problem's Scope
Using validated clinical standards, around 30% of newborns in a UK cohort study were diagnosed with eczema by the time they were one year old.
Eczema frequently manifests early; in this group, approximately 19% experienced symptoms within the first three months of life, underscoring the importance of early-life interventions.
Eczema is common in infants and young children, according to NHS guidelines, which include moisturising routines, avoiding triggers, and using steroids or barrier creams as necessary. The NHS does stress the significance of general baby nutrition and allergy evaluation, but it does not yet support gut microbiome testing as a conventional method for diagnosing or treating eczema:
https://www.nhs.uk/conditions/atopic-eczema/
How Microbiome Testing Works

Typically, microbiome testing examines the kinds and quantities of microorganisms present in a faeces sample. In babies, this can show:
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Whether "good" bacteria, such as Bifidobacterium, are present at age-appropriate amounts
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Species abundance associated with inflammation or immunological training
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Microbiome maturity in relation to developmental norms
In order to provide individualised insight that is not apparent from skin symptoms alone, testing attempts to find patterns that might connect with eczema risk or severity.
https://www.backtobalancetest.com/blogs/news/gut-microbiome-test-kit-how-it-works
Evidence of the Potential Impact of Testing and Targeted Support
Recent clinical data indicates that microbiome-guided interventions may help lower the risk of eczema in some infants, particularly those born by C-section, a population known to have different early microbiome profiles, however research on this topic is still in its infancy.
A 6-month targeted gut health support program based on microbiome testing decreased the risk of eczema in C-section babies by 83% when compared to a control group, according to a clinical trial published in Paediatric Allergy and Immunology.
Practically speaking:
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Just 6% of infants in the intervention group experienced eczema.
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In contrast, 29% of the control group
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Additionally, the program enhanced gut functions linked to essential nutrients and raised quantities of helpful bacteria like Bifidobacterium.
Although the research is yet restricted to particular groups and interventions, this study shows that early microbiome assistance based on testing can change gut bacterial patterns in ways connected to decreased eczema risk.
What You Can and Can't Learn from Testing
What microbiome analysis can assist with:
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Emphasise imbalances linked to inflammation or eczema risk;
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advise early management, particularly within the first year;
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recommend specific dietary changes or probiotics;
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and provide context that goes beyond skin complaints.
What it is unable to do:
❌ Make a direct diagnosis of eczema
❌ Assure a cure (eczema is complicated)
❌ Forecast all environmental factors or triggers
Testing is one piece of the jigsaw, not a stand-alone treatment, because eczema is caused by a combination of factors, including genetics, immunological development, environment, allergy sensitivity, and even gut-microbiome interactions.
How Microbiome Insights Are Used by Parents
When parents choose for microbiome testing, they frequently pair it with:
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Dietary recommendations to promote good bacteria
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Use probiotics strategically if tests reveal low amounts of beneficial organisms.
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Assessing allergies and avoiding them where necessary
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Enhancements in skincare and the environment
According to some study, early life microbial patterns can also be influenced by feeding practices, antibiotic exposure, vaginal versus caesarean delivery, and the early introduction of foods. Parents and professionals may take these aspects into account when analysing microbiome data. https://www.britishskinfoundation.org.uk/news/gut-bacteria-linked-with-infant-diet-eczema-and-caesarean-section-birth
NHS Advice & Practical Care
The NHS places a strong emphasis on managing eczema practically, which includes using moisturisers, identifying triggers (such as fabrics or soaps), and, if necessary, using medicinal creams under supervision. In certain instances of chronic eczema, it also suggests allergy testing. However, before microbiome testing for eczema becomes commonplace, additional research and clinical agreement are required.
See https://www.nhs.uk/conditions/atopic-eczema for official NHS information on infant eczema and when to get care.
Microbiome testing provides a more thorough examination of potential causes of baby eczema, particularly in the crucial first year when gut bacteria and immune systems are still maturing. Personalised insights can enable parents to take educated actions in addition to conventional care and assistance, even though they are not a silver bullet. A paediatrician or expert should always be consulted before making significant adjustments to your baby's care plan.
FAQs
Q. What is the gut microbiome, and how is it linked to eczema?
A. The gut microbiome is the community of bacteria in the digestive system. Early imbalances may influence immune development and inflammation linked to eczema symptoms.
Q. Can microbiome testing prevent eczema?
A. Testing can help identify microbial patterns associated with higher eczema risk, which may guide early support, but it cannot guarantee prevention on its own.
Q. Is microbiome testing available through the NHS?
A. No, microbiome testing for eczema isn’t widely offered by the NHS currently, though conventional eczema management is. https://www.nhs.uk/conditions/atopic-eczema/
Q. Does every baby with eczema have gut microbiome imbalances?
A. Not necessarily, eczema is multifactorial, and while many infants with eczema show microbial differences, this isn’t universal.
Q. Can probiotics help my baby’s eczema?
A. Some probiotic strains may support beneficial bacteria and immune function, but they should be considered based on testing and under professional guidance.
References:
https://www.frontiersin.org/journals/microbiomes/articles/10.3389/frmbi.2023.1147082/full
https://pmc.ncbi.nlm.nih.gov/articles/PMC5094743/
https://www.nhs.uk/conditions/atopic-eczema/
https://www.nejm.org/doi/full/10.1056/NEJMra074081
https://www.jacionline.org/article/S0091-6749(23)00331-7/fulltext
https://www.sciencedirect.com/science/article/abs/pii/S0190962220302991
https://pmc.ncbi.nlm.nih.gov/articles/PMC2957505/
https://pubmed.ncbi.nlm.nih.gov/37586254/
https://pmc.ncbi.nlm.nih.gov/articles/PMC3970830/
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Author: Gyanisha Gothi, ANutr AfN Registered Associate Nutritionist Gyanisha Gothi is a Registered Associate Nutritionist (ANutr) with a strong scientific background and a passion for turning complex nutrition research into practical, personalised guidance. With an MSc in Clinical and Public Health Nutrition from UCL (Merit), a BSc in Biochemistry, and additional certifications in Food Allergy & Intolerance Training and Good Clinical Practice (NIHR), she brings a well-rounded blend of academic and clinical expertise. Dedicated to evidence-based practice, Gyanisha supports individuals in improving gut health, strengthening metabolic wellbeing, and making sustainable lifestyle changes delivering a warm, client centred approach at Back to Balance. |

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